Open AccessSeroprevalence of celiac disease among children in Baghdad, Iraq
Author(s) -
Huda Sahib Abdul Mohammed Al-Rawazq,
Luay Ibraheem Al-Rawi,
Riyadh Abdul-R Al-Zubaidy
Publication year - 2020
Publication title -
international journal of research in pharmaceutical sciences
Language(s) - English
Resource type - Journals
ISSN - 0975-7538
DOI - 10.26452/ijrps.v11ispl4.4521
Subject(s) - serology , medicine , antibody , immunology , seroprevalence , gastroenterology , gliadin , diarrhea , immunoglobulin a , tissue transglutaminase , immunoglobulin e , immunoglobulin g , gluten , biology , pathology , enzyme , biochemistry
Celiac disease (CD) represents A unique disorders in which consumption of a food ingredient namely gluten-containing grains (wheat, rye, barley) in combination with genetic susceptibility is fundamental for the development of an a guilefully evolving autoimmune reaction influence the gut and other organs. The present study determines the celiac disease among suspected children. From special the laboratory for Pathogenesis Analyses in Baghdad 100 blood children samples was collected during the period from 1st March 2018 till the 31 th of July 2018, analyzed by two serological test which were Anti-tissue transglutaminase (tGT) antibodies and Anti-gliadin antibodies for the presence of serum Immunoglobulin A (IgA tGT), Immunoglobulin G (IgG tGT), Immunoglobulin A (IgA AGA), Immunoglobulin G (IgG AGA) were measured by Enzyme-linked Immunosorbent Assay (ELISA). In result obtained positive serological test Trasglutaminase (tGT) for IgA tGT was 5 (16.7 %), IgG tGT was12 (40.0 %), more than Antiglidin Antibodies IgA AGA was 3 (10.0 %), IgG AGA was 10 (33.3 %). the males was 18 (32.1 %) more than female between (6 year - 9 year) age group which represent 10 (37.0 %). The symptoms of celiac disease found with weight loss 26 (86.7 %), chronic diarrhea 21 (70.0 %), vomiting 19 (63.3 %). In this study, obtained positive serological test Trasglutaminase for (IgA, IgG tGT) Antibodies in male between age group (6 year - 9 year) and with the symptoms more found with weight loss, chronic diarrhea, vomiting.