Open AccessAnti-microbial mechanism of ZnO nanoparticles in the presence of cationic surfactant against pathogenic bacteria for pharmaceutical applications
Author(s) -
I Mary Clementia,
Kaviyarasan Raji
Publication year - 2020
Publication title -
international journal of research in pharmaceutical sciences
Language(s) - English
Resource type - Journals
ISSN - 0975-7538
DOI - 10.26452/ijrps.v11i4.4674
Subject(s) - antimicrobial , cationic polymerization , pulmonary surfactant , antibacterial activity , pathogenic bacteria , nanoparticle , zinc , materials science , bacteria , crystallite , chemistry , nanotechnology , chemical engineering , organic chemistry , biochemistry , polymer chemistry , biology , engineering , genetics , metallurgy
Metal oxide nanoparticles with quite prodigious enactment in the field of research. ZnO is considered to be an exact candidate for an antimicrobial agent. ZnO in the form of fine nanoparticles possess enhanced antibacterial action than when it is in the bulk form. It is obvious that ZnO, which have the average crystallite size in the range between 15nm to 20nm exhibits enhanced antimicrobial activity against pathogenic bacterias, so the present investigation is carried out to explains the role of cationic surfactant in the antimicrobial execution of ZnO nanoparticles enzymatic about precipitation method annealed at the temperature of 600oC. The outcomes are cogitated by XRD spectra, SEM, and Fourier Transform Infra-Red spectra. The crucial antimicrobic activity of the complex ZnO NP's antagonistic pathogenic bacterias were studied quantity-wise. ZnO nanoparticles have the capability to interfere with NorA protein, which is developed for conferring resistance in bacteria and has pumping activity that mediates the effluxing bacterias from a cell. Thus, antimicrobial effect Zinc oxide is widely used in nursing a variety of skin conditions, including dermatitis, itching due to eczema, diaper rash and acne.