Open AccessEffect of Hyaluronic Acid Cream in Management of Maxillofacial Wounds
Author(s) -
Divya Sanjeev ramakrishnan,
Sudarssansubramaniam gouthaman,
Senthilnathan Periasamy
Publication year - 2020
Publication title -
international journal of research in pharmaceutical sciences
Language(s) - English
Resource type - Journals
ISSN - 0975-7538
DOI - 10.26452/ijrps.v11i4.3672
Subject(s) - hyaluronic acid , medicine , wound healing , granulation tissue , surgery , dentistry , anatomy
The present study aims to determine the efficacy of hyaluronic acid cream in the management of maxillofacial wounds. Total of twenty-five patients who were randomly assigned to study group, was admitted in for trauma management with facial lacerations was administered hyaluronic acid cream 0.5% (BIONECT) for one week twice daily application on the wounds .the wounds were then assessed with PWAT (photographic wound assessment tool) at 3rd day, 5th day, 7th day respectively. The control group (n=25) was administered with povidone-iodine cream. The study group showed a statistically significant difference (p<0.005) in wound healing earlier than the control group at 7th day. Patient compliance was higher in the study group than the control group. Hyaluronic acid has been proven to be shown in involvement in various stages of wound healing from promoting initial inflammation, granulation tissue formation tissue, keratinocyte migration and proliferation. The hyaluronic acid cream can be utilised as an alternative to promote ideal healing by protecting the wound from detrimental changes, providing or maintaining a damp environment and remarkably reducing microbial load .hence from our study, the hyaluronic acid cream benefits in the healing of acute maxillofacial wounds.