Open AccessAntibacterial activity of Methanol and n-Hexane extracts of fruit casings of Quercus rubra against multi-drug resistance pathogenic bacteria isolated from patients with burn infection
Author(s) -
Dhafer Rahman Abed Al-janabi,
Enas Abd al-Raouf Ammar Semysim
Publication year - 2020
Publication title -
international journal of research in pharmaceutical sciences
Language(s) - English
Resource type - Journals
ISSN - 0975-7538
DOI - 10.26452/ijrps.v11i3.2643
Subject(s) - pathogenic bacteria , bacteria , antibiotics , methanol , antibacterial activity , solvent , antimicrobial , microbiology and biotechnology , traditional medicine , chemistry , biology , medicine , food science , biochemistry , organic chemistry , genetics
This study was designed to investigate the ability of methanol and extracts of fruit casings of Quercus against pathogenic bacteria isolated from patients with burn infection. Three concentrations of methanol and extracts of Quercus were done (100, 200 and 400) mg/ml. Thirty eight samples were collected from Medical Burn Center in Najaf . Males and females in different age groups. The results indicated that there were 42% , 22% , 18% , 8% E. , 6% and 4% . Seventeen antibiotics were selected in antibiotics sensitivity test. 10mg was the best antimicrobial effect. The results showed that all three concentrations had good antibacterial effect. It has also been shown that methanol solvent is more effective on bacteria than solvent. Also, the results showed that P. and S. has the highest rate of inhibition diameter with methanol solvent (38.123 ± 0.07 and 35.133 ± 0.092) mm respectively. K. was the highest rate of inhibition diameter by n- solvent 32.4 ± 0.07mm. Methanol and extracts of Quercus can be regarded as a potential antibacterial against aerobic pathogenic bacteria isolated from patients with burn infection. Therefore, Fruit casings of Quercus may be considered as a raw material for the manufacture of ointment for treatment of burns infections.