Open AccessA Review on qualification of the tablet compression machine
Author(s) -
S Avinasha,
H.V. Gangadharappa,
Hemanth Kumar S,
M. P. Gowrav
Publication year - 2020
Publication title -
international journal of research in pharmaceutical sciences
Language(s) - English
Resource type - Journals
ISSN - 0975-7538
DOI - 10.26452/ijrps.v11i2.2124
Subject(s) - manufacturing engineering , quality (philosophy) , friability , process validation , granulation , test equipment , reliability engineering , product (mathematics) , computer science , process (computing) , engineering , process engineering , engineering drawing , operations management , mathematics , materials science , verification and validation , philosophy , geometry , geotechnical engineering , epistemology , ethyl cellulose , operating system , polymer , composite material
Validation is the art of designing andpracticing the designed steps alongside with the documentation. Validation is one of themostimportant steps in maintaining &achievingthe quality of the final product group after batch. The qualification of the equipment and systems are planning to carry out the tests and record the tests. We cannot be manufacturing the product, without an equipment. If the equipment is validated, we can ensure that our product is of the top-quality. Validation of the equipment is known as Qualification. To making different kinds of dosage forms, various equipment’s are used. Here, this article concentrates on the equipment qualification for theTablet compression machine. It gives in detail, qualification steps of the equipment, which is used for the manufacturing process through wet granulation. Qualification, an ideal step for equipment validation, is the action undertaken to demonstrate the intended use and performance of the utilities and equipment.The individual steps of qualification such as design, installation, operational and performance qualification, were done in order to qualify the equipment. Blueprint of equipment validation was also included and the tablets were tested for physical parameters such asappearance, punch Shape, punch diameter, upper punch, lower punch, hardness, weight variation, friability, and thickness.