Open AccessInvestigations of the prepared polyherbal ointment for its anti-inflammatory activity
Author(s) -
M.R. Purushothaman,
H Soujanya,
S Jagadeeshwari,
Shiva Kumar K
Publication year - 2018
Publication title -
international journal of novel trends in pharmaceutical sciences
Language(s) - English
Resource type - Journals
ISSN - 2277-2782
DOI - 10.26452/ijntps.v8i1.1304
Subject(s) - oxidative stress , inflammation , traditional medicine , carrageenan , pharmacology , medicinal plants , medicine , oxidative damage , edema , drug , anti inflammatory , surgery , immunology
Inflammation is the defence response of the body to any injury or any other external agent that causes damage to the human body. Over many years there had been a rising concern for the inflammation that is caused due to the physiological stress and strain in the body due to the oxidative free radicals and oxidative damage. Medicinal plants have been used as the best treatment alternatives for the diseases in various medical systems in India and around the world. The scientific proof and validation are not authentic to that desired level. In this regard, herbs have been investigated for their pharmacological properties based on the medicinal claims and folklore claims. They had been worked by numerous amounts of research where the claims had been proven correct and published with scientific evidence. The ointment was prepared using the extracts of the plant Salvia and the activity was attributed to the phytosterols, and by inhibiting the prostaglandin synthesis. The activity was comparable to the standard drug and the extracts and showed better activity. The activity exhibited by the ointment was very rapid and enhanced the healing of the paw edema, which was induced by carrageenan.