Open AccessElectrical and viscoelastic parameters of erythrocytes in patients with different degrees of arterial hypertension
Author(s) -
Andrey Gromov,
М. В. Кручинина,
А В Рабко,
В.А. Баум,
В. М. Генералов
Publication year - 2012
Publication title -
sistemnye gipertenzii
Language(s) - English
Resource type - Journals
eISSN - 2542-2189
pISSN - 2075-082X
DOI - 10.26442/sg28946
Subject(s) - microalbuminuria , viscoelasticity , medicine , erythrocyte deformability , red blood cell , cardiology , inflammation , endothelial dysfunction , endocrinology , disease , materials science , composite material
We investigated the electrical and viscoelastic parameters of red blood cells in patients with hypertension of 1 and 2 degree. We marked the increase of variations in the characteristics of red blood cells with an increase in the degree of hypertension. We identified the correlations of erythrocytes parameters with biochemical indicators reflecting hyperlipidemia, microalbuminuria and the presence of inflammation. It was noted that the velocity of red blood cells to the electrodes, the dipole moment can be the markers of initial stages of endothelial dysfunction. It was suggested that the decrease of deformability, surface charge of red blood cells are the important pathogenetic factors in the progression of hypertension, therefore, requires additional emphasis in the treatment of this disease.