Open AccessHypertension treatment: Is there a place for b-adrenoblockers?
Author(s) -
Л. О. Минушкина
Publication year - 2013
Publication title -
sistemnye gipertenzii
Language(s) - English
Resource type - Journals
eISSN - 2542-2189
pISSN - 2075-082X
DOI - 10.26442/sg28945
Subject(s) - nebivolol , medicine , drug , pharmacology , mechanism (biology) , antihypertensive drug , function (biology) , essential hypertension , pharmacotherapy , cardiology , blood pressure , biology , philosophy , epistemology , evolutionary biology
The paper considers whether b-adrenoblockers may be used in the therapy of hypertension. It views in more detail the specific features of nebivolol, a third-generation highly selective b-adrenoblocker that has properties of acting on endothelial function and stimulating NO synthesis. The possible mechanism for the angioprotective activity of the drug is described. There is evidence for its antihypertensive efficacy. The effect of nebivolol on target organs in hypertension, its metabolic effects, and the possibilities of using the drug in patients with comorbidities are considered.