Open AccessBiochemical predictors of coronary atherosclerosis in patients with metabolic disorders
Author(s) -
Е.М. Суркичин,
Суркичин Елена Михайловна,
И.П. Шуваев,
Шуваев Игорь Петрович,
Э.У. Асымбекова,
Асымбекова Эльмира Уметовна,
С.Т. Мацкеплишвили,
Мацкеплишвили Симон Тэймуразович
Publication year - 2015
Publication title -
cardiosomatika
Language(s) - English
Resource type - Journals
eISSN - 2658-5707
pISSN - 2221-7185
DOI - 10.26442/cs45138
Subject(s) - adiponectin , adipokine , metabolic syndrome , pathological , medicine , adipose tissue , leptin , pathogenesis , endocrine system , insulin resistance , diabetes mellitus , coronary atherosclerosis , endocrinology , obesity , bioinformatics , coronary heart disease , biology , hormone
Metabolic syndrome represents a combination of different major risk factors of cardiovascular diseases and is mainly related to impaired insulin sensitivity in biological tissues. Common understanding of pathogenesis and relationship of different pathological conditions within metabolic syndrome is still missing. New data on endocrine function of adipose tissue suggests that development and progression of atherosclerosis in this situation may be related to adipokines dysbalance. This study investigates correlation of leptin and adiponectin with clinical and laboratory changes in patients with metabolic disorders.