Open AccessCalcium antagonist lercanidipine in hypertension
Author(s) -
Г. А. Барышникова,
Барышникова Галина Анатольевна,
S A Chorbinskaya,
Чорбинская Светлана Алексеевна,
I I Stepanova,
Степанова Ирина Ираклиевна
Publication year - 2014
Publication title -
cardiosomatika
Language(s) - English
Resource type - Journals
eISSN - 2658-5707
pISSN - 2221-7185
DOI - 10.26442/cs45046
Subject(s) - lercanidipine , medicine , blood pressure , calcium , antagonist , cardiology , peripheral edema , left ventricular hypertrophy , heart rate , pharmacology , anesthesia , adverse effect , receptor
The article presents the results of studies on the effectiveness and safety of a III generation calcium antagonist lercanidipine in the treatment of hypertension. Lercanidipine treatment leads to a marked significant reduction in systolic and diastolic blood pressure without producing a significant effect on heart rate. The drug has organ-protective effect, reduces left ventricular hypertrophy, improves kidney function and has antiproteinuric action. Lercanidipine is well tolerated, less likely to cause peripheral edema compared with other calcium antagonists.