Correction of cardiovascular disorders in diabetic patients with depressive simptoms | Zendy

M. I. Kolyadich | Zendy; И. И. Шапошник | Zendy

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Correction of cardiovascular disorders in diabetic patients with depressive simptoms

Author(s) -

M. I. Kolyadich,

И. И. Шапошник

Publication year - 2013

Publication title -

cardiosomatics

Language(s) - English

Resource type - Journals

eISSN - 2658-5707

pISSN - 2221-7185

DOI - 10.26442/cs44990

Subject(s) - lipoic acid , diabetes mellitus , medicine , circadian rhythm , depressive symptoms , endocrinology , cardiology , chemistry , biochemistry , antioxidant

We studied the influence of mexidol and a-lipoic acid on cardiovascular and affective disorders' severity in patients with diabetes. 14-day administration of mexidol (300 mg/day) and a-lipoic acid (600 mg/day) had a positive impact on depressive guilt dinamics in association with a decrease in QTn-interval duration. Moreover, mexidol decreased patients' propencity to postural hypotension, and alfa-lipoic acid corrected myocardial diastolic function, pulmonary blood flow and circadian glycemia.

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