Open AccessCorrection of cardiovascular disorders in diabetic patients with depressive simptoms
Author(s) -
M I Kolyadich,
Колядич Мария Ильинична,
И. И. Шапошник,
Шапошник Игорь Иосифович
Publication year - 2013
Publication title -
cardiosomatika
Language(s) - English
Resource type - Journals
eISSN - 2658-5707
pISSN - 2221-7185
DOI - 10.26442/cs44990
Subject(s) - lipoic acid , diabetes mellitus , medicine , circadian rhythm , depressive symptoms , endocrinology , cardiology , chemistry , biochemistry , antioxidant
We studied the influence of mexidol and a-lipoic acid on cardiovascular and affective disorders' severity in patients with diabetes. 14-day administration of mexidol (300 mg/day) and a-lipoic acid (600 mg/day) had a positive impact on depressive guilt dinamics in association with a decrease in QTn-interval duration. Moreover, mexidol decreased patients' propencity to postural hypotension, and alfa-lipoic acid corrected myocardial diastolic function, pulmonary blood flow and circadian glycemia.