Open AccessRol' polimorfizma gena konneksina 40v geneze nasledstvennogo sindroma slabostisinusovogo uzla
Author(s) -
Svetlana Yur'evikulina,
Никулина Светлана Юрьевна,
А. А. Чернова,
Чернова Анна Александровна,
В. А. Шульман,
Шульман Владимир Абрамович,
Т. С. Кукушкина,
Кукушкина Татьяна Сергеевна,
М. И. Воевода,
Воевода Михаил Иванович,
В. Н. Максимов,
Максимов Владимир Николаевич
Publication year - 2011
Publication title -
cardiosomatika (print)
Language(s) - English
Resource type - Journals
eISSN - 2658-5707
pISSN - 2221-7185
DOI - 10.26442/cs44967
Subject(s) - sss* , polymorphism (computer science) , genotype , connexin , medicine , genetics , gene , biology , gastroenterology , gap junction , intracellular
Summary. In this study for the first time on clinical-genetic material an association of the hereditary sick sinussyndrome (SSS) with the connexin 40 gene polymorphism was found.For the first time it was revealed that the heterozygous variant of connexin 40 gene genotype was significantly morecommon in patients with SSS and their healthy relatives in comparison with subjects of the control group.