Open AccessHypertrophic cardiomyopathy: a modern view of the problem
Author(s) -
Amina M. Alieva,
Алиева Амина Магомедовна,
И. И. Алмазова,
Алмазова Ильда Исмаиловна,
Е. В. Резник,
Резник Елена Владимировна,
Т. В. Пинчук,
Пинчук Татьяна Витальевна,
Irina E. Baykova,
Байкова Ирина Евгеньевна,
V. A. Kislyakov,
Кисляков Владимир Аркадьевич,
В. И. Светлаков,
Светлаков Вячеслав Игоревич,
Irina V. Kovtyukh,
Ковтюх Ирина Владимировна,
Sergey A. Korvyakov,
Корвяков Сергей Александрович,
Alik M. Rakhaev,
Рахаев Алик Магомедович,
И. Г. Никитин,
Никитин Игорь Геннадьевич
Publication year - 2020
Publication title -
cardiosomatika
Language(s) - English
Resource type - Journals
eISSN - 2658-5707
pISSN - 2221-7185
DOI - 10.26442/22217185.2020.1.200116
Subject(s) - hypertrophic cardiomyopathy , medicine , etiology , disease , sudden cardiac death , cardiomyopathy , cardiology , pathophysiology , heart disease , sudden death , left ventricular hypertrophy , intensive care medicine , heart failure , blood pressure
Hypertrophic cardiomyopathy (HCM) is the most common genetic heart disease, with a prevalence of approximately 1 in 500 among the adult cohort. It is a common etiological factor of sudden cardiac death in the young and a common cause of morbidity and mortality in all age groups. HCM is characterized by a complex pathophysiology, which is manifested by a heterogeneous clinical picture. The mechanism of development of this variant of hypertrophy is not fully understood. Currently, only a part of the genetic mutations that correlate with the development of this pathology has been identified. In this regard, the issue of genetic diagnosis of HCM is very relevant, as it will allow us to conduct advanced screening. A very important task is to develop a personalized approach in the conservative and surgical treatment of people suffering from this variant of cardiopathy.