Open AccessChanges in markers of hematological, biochemical and coagulological blood tests with coronavirus COVID-19 infections
Author(s) -
Р. Ю. Абдуллаев,
Oksana Komissarova
Publication year - 2020
Publication title -
consilium medicum
Language(s) - English
Resource type - Journals
eISSN - 2542-2170
pISSN - 2075-1753
DOI - 10.26442/20751753.2020.11.200369
Subject(s) - fibrinolysis , ferritin , covid-19 , hemostasis , d dimer , coronavirus , albumin , medicine , fibrinogen , immunology , hematology , disease , infectious disease (medical specialty)
This review provides new literature data on the features of changes in the indicators of clinical and biochemical analysis of blood, as well as hemostatic and fib-rinolysis systems in patients with coronavirus infection COVID-19. It was shown that laboratory manifestations of COVID-19 have their own characteristics and are closely interrelated with the nature of the course of infection. In a clinical blood test, lymphopenia and thrombocytopenia are most common. Among the bio-chemical parameters of blood, an increase in the level of C-reactive protein and ferritin, as well as a decrease in the level of albumin, are more often detected. It should be noted that in 1/3 of severe patients with COVID-19 infection, the activity of liver enzymes, ALT and AST, increases. Among the indicators of hemostasis and fibrinolysis systems, an increase in the concentration of D-dimer in blood plasma is more often detected. The review also analyzes the possible causes of changes in some laboratory parameters with COVID-19.