Open AccessSoy protein as part of a low-protein diet is a new direction in cardio- and nephroprotection in patients with 3B–4 stages of chronic kidney disease: prospective, randomized, controlled clinical study
Author(s) -
Ludmilа Milоvаnоvа,
Marina Taranova,
А. В. Волков,
Svetlana Milоvаnova,
Vladimir Beketov
Publication year - 2022
Publication title -
terapevtičeskij arhiv
Language(s) - English
Resource type - Journals
eISSN - 2309-5342
pISSN - 0040-3660
DOI - 10.26442/00403660.2022.06.201567
Subject(s) - medicine , kidney disease , renal hypertrophy , soy protein , animal studies , cardioprotection , randomized controlled trial , prospective cohort study , kidney , renal function , low protein diet , muscle hypertrophy , body mass index , endocrinology , gastroenterology , pathology , ischemia , diabetic nephropathy
It has been established that the use of a low-protein diet (LPD) in combination with ketoanalogues (KA) of essential amino acids can contribute to cardio- and nephroprotection in chronic kidney disease (CKD). Moreover, it has been shown that replacing part of the animal protein with soy protein (SP) in the diet contributed to more pronounced nephro- and cardioprotection in CKD, however, the data, available in the literature, are mainly represented by experimental studies.