Myocardial scintigraphy with <sup>99m</sup>Tc-pyrophosphate in the diagnosis of cardiac amyloidosis: place in the diagnostic algorithm, features of the implementation and interpretation of the study
Author(s) -
А. А. Аншелес,
S. N. Nasonova,
И. В. Жиров,
М. А. Саидова,
О. В. Стукалова,
С. Н. Терещенко,
В. Б. Сергиенко
Publication year - 2022
Publication title -
terapevticheskii arkhiv
Language(s) - English
Resource type - Journals
eISSN - 2309-5342
pISSN - 0040-3660
DOI - 10.26442/00403660.2022.04.201461
Subject(s) - medicine , pyrophosphate , cardiac amyloidosis , amyloidosis , scintigraphy , algorithm , interpretation (philosophy) , technetium 99 , nuclear medicine , nuclear magnetic resonance , linguistics , physics , computer science , enzyme , philosophy
The article summarizes the current experience of the nuclear medicine department of the Chazov National Medical Research Center of Cardiology in the implementation of myocardium scintigraphy with 99mTc-pyrophosphate with the differential diagnosis of the types of cardiac amyloidosis. Causes of false-positive, equivocal and non-diagnostic results, are analyzed. Possible ways to eliminate mistakes, including by modifying protocols of planar and tomographic research and optimizing the whole diagnostic algorithm for amyloidosis of the heart, are discussed.
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