Open AccessMethotrexate-induced lung damage in a patient with rheumatoid arthritis
Author(s) -
L. A. Ponomareva,
Пономарева Любовь Андреевна,
Daria V. Gurova,
Гурова Дарья Владимировна,
Е Н Попова,
Попова Елена Николаевна,
Natalia Chebotareva,
Чеботарева Наталья Викторовна,
И. Б. Бондаренко,
Бондаренко Инна Борисовна,
Sergey Moiseev,
Моисеев Сергей Валентинович
Publication year - 2021
Publication title -
terapevtičeskij arhiv
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.181
H-Index - 14
eISSN - 2309-5342
pISSN - 0040-3660
DOI - 10.26442/00403660.2021.03.200656
Subject(s) - medicine , rheumatoid arthritis , methotrexate , interstitial lung disease , lung , pneumonitis , disease , arthritis , differential diagnosis , lung disease , pathology
We herein report a case of interstitial lung disease secondary to the use of methotrexate in a patient with rheumatoid arthritis. Differential diagnosis between pneumonitis caused by methotrexate in patients treated with basic methotrexate therapy and interstitial pulmonary disease associated with rheumatoid arthritis is based on the clinical examination and instrumental data. The main condition for favorable clinical outcome in all drug-induced lung disease is drug withdrawal, what was proven in our report.