Open AccessLaboratory diagnostics in medicine
Author(s) -
А. Г. Кочетов,
Кочетов Анатолий Глебович,
O. V. Lyang,
Лянг Ольга Викторовна,
Irina Zhirova,
Жирова Ирина Алексеевна,
O. O. Ivoilov,
Ивойлов Олег Олегович
Publication year - 2020
Publication title -
terapevtičeskij arhiv
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.181
H-Index - 14
eISSN - 2309-5342
pISSN - 0040-3660
DOI - 10.26442/00403660.2020.04.000501
Subject(s) - medicine , medical laboratory , medical physics , probabilistic logic , interpretation (philosophy) , predictive value , intensive care medicine , management science , risk analysis (engineering) , pathology , artificial intelligence , computer science , economics , programming language
The development of clinical laboratory diagnostics is in line with the evidence-based medicine, which requires that clinical decisions have to be based on diagnostic methods with proven informativity. This creates a request for the scientific validity of the use of laboratory researches and application of probabilistic interpretation tools corresponding to the tasks. The concept of indefiniteness (analytical, biological and clinical) is at the heart of interpretation of laboratory results. The inclusion of laboratory research in clinical guidelines, the choice and appointment of this research to the patient should not be made from the position of ideas about increasing or decreasing the laboratory index in the disease, but on the basis of its scientifically proven characteristics as a laboratory biomarker sensitivity, specificity, predictive value, as well as the relationship with certain clinical events, outcomes, risks. These characteristics are probabilistic and can be defined.