Open AccessHepatitis C virus - related cryoglobulinemic vasculitis with renal involvement current possibilities of diagnostic and treatment
Author(s) -
Svetlana Milоvаnova,
L V Kozlovskaya,
Ludmilа Milоvаnоvа,
N B Gordovskaya,
Т М Игнатова,
Marina Taranova,
Т В Андросова
Publication year - 2019
Publication title -
terapevtičeskij arhiv
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.181
H-Index - 14
eISSN - 2309-5342
pISSN - 0040-3660
DOI - 10.26442/00403660.2019.06.000254
Subject(s) - medicine , cryoglobulinemia , vasculitis , hepatitis c virus , cryoglobulins , immunology , hepatitis c , systemic vasculitis , pathology , virus , antibody , disease
The extrahepatic manifestations of HCV infections, which include mixed cryoglobulinemia (MC), are important for prognosis and determination of the treatment options of these patients. Currently, mixed MC type II is considered as a specific marker of chronic HCV infection. Kidney damage is one of the severe, often determining a prognosis of extrahepatic manifestation of HCV-associated cryoglobulinemic vasculitis. The review discusses the current diagnostic approaches to cryoglobulinemic GN, as well as perspectives for improving antiviral and pathogenetic therapy.