Open Access5-HT3 Antagonist for Pregnancy Associated Nausea and Vomiting
Author(s) -
Sumit Ghosh,
Nirankar Dev,
David Matthews
Publication year - 2021
Publication title -
international healthcare research journal
Language(s) - English
Resource type - Journals
ISSN - 2456-8090
DOI - 10.26440/ihrj/0509.12485
Subject(s) - ondansetron , nausea , vomiting , pregnancy , medicine , obstetrics , hyperemesis gravidarum , drug , anesthesia , first trimester , fetus , pharmacology , genetics , biology
5-HT3 antagonists appear to be an effective treatment option in the treatment of nausea and vomiting associated with pregnancy. Literature suggests an increased risk of congenital defects in fetuses exposed to ondansetron during pregnancy, especially during first trimester. Health authorities now suggest that this drug should not be used during this period. However, this decision is debatable and whether ondansetron can be used in pregnant women is still controversial.