Open AccessHuman Papilloma Virus – neonatal involvement
Author(s) -
Simona Popescu,
Andreea Mădălina Bănică,
Simona Vlădăreanu,
Radu Vlădăreanu
Publication year - 2018
Publication title -
ginecologia.ro
Language(s) - English
Resource type - Journals
eISSN - 2457-3566
pISSN - 2344-2301
DOI - 10.26416/gine.20.2.2018.1717
Subject(s) - recurrent respiratory papillomatosis , medicine , pregnancy , human papilloma virus , transmission (telecommunications) , population , virus , epidemiology , cohort , pediatrics , obstetrics , papilloma , immunology , virology , cervical cancer , pathology , biology , cancer , environmental health , genetics , electrical engineering , engineering
Aims . Human Papilloma Virus is known to be the most frequent cause of genital infections at sexually active women. The virus is transmitted mainly sexually but epidemiological and clinical data suggest sufficient evidence also for other routes of transmission. Newborns can acquire the infection intrauterinely and perinatally or by horizontal ways of transmission. We aimed to describe, by reviewing the literature, the damaging effect of HPV on pregnancy outcomes and the risk of the newborn to develop recurrent respiratory papillomatosis. Also, we assessed the risk of HPV bivalent and quadrivalent vaccine in pregnancy and paediatric population. Method . We carried out an electronic database search, such as Pubmed, Medline, Google Scholar, for articles including “Human Papilloma Virus”, “perinatal transmission”, “recurrent respiratory papillomatosis”, “HPV vaccine”, “pregnancy outcomes”. We selected articles published between 2015 and 2018. Conclusions . The main mode of transmission from mother to newborn occurs during pregnancy and at the time of delivery. The virus can also be transmitted among the family members by close contact. There is insufficient data to conclude about the impact of Human Papilloma Virus on pregnancy and on the newborn, so for a relevant understanding more research for a long term and with an extended cohort is needed.