
Paracetamol during pregnancy: how safe is it?
Author(s) -
Mihaela Boț,
Adriana Tecuci,
Aida Petca,
Mona Elena Zvâncă,
Simona Vlădăreanu
Publication year - 2018
Publication title -
ginecologia.ro
Language(s) - English
Resource type - Journals
eISSN - 2457-3566
pISSN - 2344-2301
DOI - 10.26416/gine.20.2.2018.1711
Subject(s) - pregnancy , acetaminophen , medicine , antipyretic , analgesic , autism , neurodevelopmental disorder , genitourinary system , fetus , anesthesia , obstetrics , pediatrics , psychiatry , genetics , biology
Acetaminophen (paracetamol) is the most commonly used analgesic and antipyretic during pregnancy. Research suggests that acetaminophen use in pregnancy is associated with abnormal fetal neurodevelopment (an increased risk for neurodevelopmental impairment − ADHD, autism and hyperactivity symptoms). Paracetamol causes language delay (less than 50 words at 30 months of age). Other recent studies describe the association of urogenital male malformations after prenatal paracetamol exposure.