Open AccessImpact of DNA-Encoded Chemical Library Technology on Drug Discovery
Author(s) -
Michelle Keller,
Kristina Schira,
Jörg Scheuermann
Publication year - 2022
Publication title -
chimia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 55
eISSN - 2673-2424
pISSN - 0009-4293
DOI - 10.2533/chimia.2022.388
Subject(s) - drug discovery , nanotechnology , perspective (graphical) , pharmaceutical industry , computational biology , chemistry , business , computer science , biology , microbiology and biotechnology , materials science , biochemistry , artificial intelligence
DNA-Encoded Chemical Libraries (DELs) have gained momentum over the recent years for the discovery of small-molecule ligands and the technology has been integrated in most of the larger pharmaceutical companies. With this perspective we would like to summarize the development of DEL technology and present some representative DEL-derived hits which may soon enter the pharmaceutical market.