Open AccessCopper, Boron and Vinyl Epoxides: from 1,4-Diols to Cyclopropylboronates
Author(s) -
Luis Nóvoa,
Laura Trulli,
Alejandro Parra,
Mariola Tortosa
Publication year - 2020
Publication title -
chimia
Language(s) - English
Resource type - Journals
eISSN - 2673-2424
pISSN - 0009-4293
DOI - 10.2533/chimia.2020.852
Subject(s) - epoxide , alkene , allylic rearrangement , boron , chemistry , copper , reactivity (psychology) , organic chemistry , diol , polymer chemistry , catalysis , medicine , alternative medicine , pathology
Herein we describe the reactivity found between vinyl epoxides and catalytically generated copper-boryl complexes. By tuning the substituents of the alkene and/or the reaction conditions, 1,4-diols, allylic alcohols or cyclopropylboronates can be prepared. The stereochemical information of the vinyl epoxide is transferred to the products with high levels of stereocontrol.