Open AccessTHQphos in Ir-catalyzed Asymmetric Allylic Substitution Reactions
Author(s) -
Xiao Zhang,
ShuLi You
Publication year - 2018
Publication title -
chimia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 55
eISSN - 2673-2424
pISSN - 0009-4293
DOI - 10.2533/chimia.2018.589
Subject(s) - allylic rearrangement , iridium , substitution (logic) , catalysis , substitution reaction , chemistry , enantioselective synthesis , combinatorial chemistry , organic chemistry , computer science , programming language
The 1,2,3,4-tetrahydroquinoline phosphoramidites (THQphos) have been found to be efficient ligands for iridium-catalyzed asymmetric allylic substitution reactions. In this short review article, an overall introduction on the development of THQphos, involving their original design, preparation, mechanistic studies, applications and features will be described.