Open AccessBioinspired Catalytic Generation of Main-group Electrophiles by Cooperative Bond Activation
Author(s) -
Francis M. Forster,
Martin Oestreich
Publication year - 2018
Publication title -
chimia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 55
eISSN - 2673-2424
pISSN - 0009-4293
DOI - 10.2533/chimia.2018.584
Subject(s) - heterolysis , electrophile , catalysis , ruthenium , chemistry , cooperativity , cationic polymerization , ligand (biochemistry) , combinatorial chemistry , group (periodic table) , nanotechnology , materials science , polymer chemistry , organic chemistry , biochemistry , receptor
Catalytic processes involving cooperativity have seen tremendous progress in recent years and impressive new synthetic methodologies have been developed. Inspired by the cooperative heterolytic H2 splitting in [NiFe] hydrogenases, Ohki and Tatsumi designed cationic ruthenium thiolate complexes with a tethered sulfur ligand. Over the last decade, we have demonstrated the facile activation of main-group hydrides such as hydrosilanes, hydroboranes, DIBAL–H, and hydrostannanes by the Ru–S bond in Ohki–Tatsumi complexes. This account illustrates these E–H bond activations and highlights selected catalytic applications, particularly dehydrocouplings, of the generated main-group electrophiles.