Open AccessMesoporous Silica for Triphase Nucleophilic Substitution Reactions
Author(s) -
Shouai Feng,
Yixin Li,
Hong Liu,
Jiaqi Huang,
Chang Ji,
Liang Qiao,
Baohong Liu,
Ji Ji
Publication year - 2018
Publication title -
chimia
Language(s) - English
Resource type - Journals
eISSN - 2673-2424
pISSN - 0009-4293
DOI - 10.2533/chimia.2018.514
Subject(s) - catalysis , mesoporous silica , nucleophile , nucleophilic substitution , phase (matter) , amphiphile , mesoporous material , chemistry , substitution reaction , reaction rate , phase transfer catalyst , chemical engineering , organic chemistry , combinatorial chemistry , materials science , copolymer , polymer , engineering
Mesoporous silica SBA-15 is shown to be a very efficient alternative to phase transfer catalyst salts for two-phase nucleophilic substitutions. The two-phase reaction can efficiently take place in the absence of PTCs. The high catalytic activity and reaction rates can be attributed to the amphiphilic and negatively charged surface of SBA-15 as well as the rapid ingress of the reactants and egress of the products.