Open AccessImproving Sensitivity of Solid-state NMR Spectroscopy by Rational Design of Polarizing Agents for Dynamic Nuclear Polarization
Author(s) -
Dominik Kubicki,
Lyndon Emsley
Publication year - 2017
Publication title -
chimia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 55
eISSN - 2673-2424
pISSN - 0009-4293
DOI - 10.2533/chimia.2017.190
Subject(s) - polarization (electrochemistry) , nuclear magnetic resonance spectroscopy , solid state , relaxation (psychology) , spectroscopy , dielectric , solid state nuclear magnetic resonance , materials science , rational design , chemistry , electronic structure , nuclear magnetic resonance , chemical physics , optoelectronics , nanotechnology , computational chemistry , stereochemistry , physics , psychology , social psychology , quantum mechanics
We review our recent efforts to optimize the efficiency of polarizing agents for Dynamic Nuclear Polarization (DNP) in solid-state MAS NMR spectroscopy. We elucidate the links between DNP performance, molecular structure and electronic relaxation properties of dinitroxide biradicals. We show that deuteration and increased bulkiness lead to slower electronic relaxation and in turn to higher DNP enhancements. We also show that the incorporation of solid dielectric particles into the sample is a general method of amplifying DNP enhancements by about a factor of two.