Open AccessFunctionalization of Glycals Leading to 2-Deoxy-O-glycosides, Aminosugars, Nitrosugars and Glycosidase Inhibitors: Our Experience
Author(s) -
Rima Lahiri,
D. Suresh,
Yashwànt D. Vankar
Publication year - 2012
Publication title -
chimia
Language(s) - English
Resource type - Journals
eISSN - 2673-2424
pISSN - 0009-4293
DOI - 10.2533/chimia.2012.905
Subject(s) - glycoside hydrolase , chemistry , glycopeptide , glycoside , surface modification , combinatorial chemistry , stereochemistry , organic chemistry , enzyme , biochemistry , antibiotics
Glycals have been transformed into a variety of functionalized substrates which have been found to be useful in synthesizing some aminosugars, N-glycopeptides, nitrosugars and some iminosugars which are potential glycosidase inhibitors. An account of work that has been done in our laboratory is briefly discussed here.