Open AccessRadical Carbon–Carbon Bond Formations Enabled by Visible Light Active Photocatalysts
Author(s) -
CarlJohan Wallentin,
John D. Nguyen,
Corey R. J. Stephenson
Publication year - 2012
Publication title -
chimia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 55
eISSN - 2673-2424
pISSN - 0009-4293
DOI - 10.2533/chimia.2012.394
Subject(s) - photoredox catalysis , photochemistry , chemistry , photocatalysis , catalysis , radical , halogenation , halogen , carbon fibers , intermolecular force , visible spectrum , redox , combinatorial chemistry , organic chemistry , materials science , molecule , composite number , alkyl , optoelectronics , composite material
This mini-review highlights the Stephenson group's contribution to the field of photoredox catalysis with emphasis on carbon–carbon bond formation. The realization of photoredox mediated reductive dehalogenation initiated investigations toward both intra- and intermolecular coupling reactions. These reactions commenced via visible light-mediated reduction of activated halogens to give carbon-centered radicals that were subsequently involved in carbon–carbon bond forming transformations. The developed protocols using Ru and Ir based polypyridyl complexes as photoredox catalysts were further tuned to efficiently catalyze overall redox neutral atom transfer radical addition reactions. Most recently, a simplistic flow reactor technique has been utilized to affect a broad scope of photocatalytic transformations with significant enhancement in reaction efficiency.