Open AccessSyntheses and Biological Activities of 1,4-Iminoalditol Derivatives as ?-L-Fucosidase Inhibitors
Author(s) -
Elena MorenoClavijo,
Ana T. Carmona,
Ângelo Vargas,
Lidia Molina,
Inmaculada Robina
Publication year - 2011
Publication title -
chimia
Language(s) - English
Resource type - Journals
eISSN - 2673-2424
pISSN - 0009-4293
DOI - 10.2533/chimia.2011.40
Subject(s) - pyrrolidine , chemistry , fucosidase , combinatorial chemistry , stereochemistry , biochemistry , glycoprotein , fucose
A review dealing with 1,4-iminoalditol (hydroxylated pyrrolidine) derivatives as inhibitors of ?-L-fucosidases including the different synthetic approaches for their preparation as well as their inhibitory properties is presented.