Open AccessIridium-Catalyzed Isomerization of Primary Allylic Alcohols
Author(s) -
Luca Mantilli,
Clément Mazet
Publication year - 2009
Publication title -
chimia
Language(s) - English
Resource type - Journals
eISSN - 2673-2424
pISSN - 0009-4293
DOI - 10.2533/chimia.2009.35
Subject(s) - isomerization , iridium , allylic rearrangement , catalysis , primary (astronomy) , reactivity (psychology) , chemistry , photochemistry , organic chemistry , physics , medicine , alternative medicine , pathology , astronomy
A readily accessible iridium hydrogenation catalyst displays high reactivity for the isomerization of primary allylic alcohols under mild reaction conditions. Key to the efficiency of the catalytic system is to deviate from the conventional hydrogenation route in favor of the desired isomerization pathway by adequately tuning the reaction conditions as indicated by preliminary mechanistic investigations