Open AccessBiologically Relevant Small Radicals
Author(s) -
Georg Bauer,
Chryssostomos Chatgilialoglu,
Jerzy Gȩbicki,
Lidia Gębicka,
Georg Gescheidt,
Bernard T. Golding,
Sara Goldstein,
József Kaizer,
Gábor Merényi,
Gábor Speier,
Peter Wardman
Publication year - 2008
Publication title -
chimia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 55
eISSN - 2673-2424
pISSN - 0009-4293
DOI - 10.2533/chimia.2008.704
Subject(s) - radical , biomolecule , reactivity (psychology) , chemistry , organic chemistry , biochemistry , medicine , alternative medicine , pathology
Biologically relevant small radicals are at the focus of the working group 4 (WG4) of the COST Action CM0603 (Free Radicals in Chemical Biology, CHEMBIORADICAL). This article surveys the areas of research being undertaken by the partners in WG4. The character of the radicals is described together with experimental techniques utilized to follow their structure and reactivity. Specifically, C-, S-, N- and O-centered radicals of small size, and their interaction with different biomolecules are described. Processes at the molecular level exemplifying important biological signaling and damaging pathways are introduced.