Open AccessCD Methods Development at the Bio-Nano Interface
Author(s) -
Andréas Hennig,
Sheshanath V. Bhosale,
Naomi Sakai,
Stefan Matile
Publication year - 2008
Publication title -
chimia
Language(s) - English
Resource type - Journals
eISSN - 2673-2424
pISSN - 0009-4293
DOI - 10.2533/chimia.2008.493
Subject(s) - exergonic reaction , nanotechnology , circular dichroism , nano , supramolecular chemistry , chemistry , nanobiotechnology , materials science , biophysics , molecule , crystallography , biology , biochemistry , nanoparticle , organic chemistry , composite material , catalysis
We describe recent applications of circular dichroism (CD) spectroscopy to develop simple methods for the study of supramolecular functional materials. Examples include the development of a CD method to identify supramolecules in action (and to determine Hill coefficients for exergonic self-assembly), or CD methods to measure osmotic pressure and the activity of ion channels and pores. For the latter two applications, G-quartets are introduced as versatile functional CD probes in chirogenic vesicles