Preparation and Synthetic Applications of 8-Oxabicyclo[3.2.1]oct-6-en-3-one Derivatives | Zendy

Sylvain Favre | Zendy; Sandrine GerberLemaire | Zendy; Pierre Vogel | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Preparation and Synthetic Applications of 8-Oxabicyclo[3.2.1]oct-6-en-3-one Derivatives

Author(s) -

Sylvain Favre,

Sandrine GerberLemaire,

Pierre Vogel

Publication year - 2008

Publication title -

chimia international journal for chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.387

H-Index - 55

eISSN - 2673-2424

pISSN - 0009-4293

DOI - 10.2533/chimia.2008.221

Subject(s) - synthon , desymmetrization , stereoselectivity , chemistry , total synthesis , combinatorial chemistry , stereochemistry , resolution (logic) , enantioselective synthesis , organic chemistry , computer science , programming language , catalysis

The development of efficient routes to multi-gram quantities of chiral synthons is a key issue in the total synthesis of natural products and analogues. The conformationally defined and rigid 8-oxabicyclo[3.2.1]oct-6-en-3-one template is an appealing starting material for the development of non-iterative approaches to polyoxygenated fragments that are found in a large variety of biologically relevant natural compounds. Desymmetrization and resolution procedures, stereoselective functionalizations and double-chain elongations represent attractive strategies for such synthetic challenges.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research