Open AccessDesign of C2-Symmetric Chiral Phase-transfer Catalysts for Practical Asymmetric Synthesis
Author(s) -
Keiji Maruoka
Publication year - 2007
Publication title -
chimia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 55
eISSN - 2673-2424
pISSN - 0009-4293
DOI - 10.2533/chimia.2007.263
Subject(s) - catalysis , enantioselective synthesis , phase (matter) , combinatorial chemistry , ammonium , chemistry , molecule , chirality (physics) , organic chemistry , materials science , chiral symmetry , physics , quantum mechanics , nambu–jona lasinio model , quark
A series of structurally rigid, chiral quaternary ammonium salts derived from commercially available (S)- or (R)-1,1?-bi-2-naphthol have been designed as new C2-symmetric chiral phase-transfer catalysts. These chiral organocatalysts have been successfully applied to the highly practical asymmetric synthesis of useful organic molecules including amino acid derivatives.