(S)- and (R)-5-Pyrrolidin-2-yl-1H-tetrazoles: Enantiomeric Organocatalysts of Broad Utility in Organic Synthesis | Zendy

Deborah A. Longbottom | Zendy; V. Franckevicius | Zendy; Steven V. Ley | Zendy

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(S)- and (R)-5-Pyrrolidin-2-yl-1H-tetrazoles: Enantiomeric Organocatalysts of Broad Utility in Organic Synthesis

Author(s) -

Deborah A. Longbottom,

V. Franckevicius,

Steven V. Ley

Publication year - 2007

Publication title -

chimia international journal for chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.387

H-Index - 55

eISSN - 2673-2424

pISSN - 0009-4293

DOI - 10.2533/chimia.2007.247

Subject(s) - enantiomer , catalysis , organocatalysis , enantioselective synthesis , chemistry , organic synthesis , combinatorial chemistry , enantiomeric excess , organic chemistry

This mini-review concerns the broad application of (S)- and (R)-5-pyrrolidin-2-yl-l H-tetrazoles as organocatalysts. A summary of methods for their synthesis is followed by a discussion of the general reaction mechanism and subsequent analysis of each reaction type for which they have proved to be efficient catalytic species. Where relevant, a comparison is made with other organocatalysts in similar asymmetric reaction processes

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