Open AccessOrganocatalysis in the Asymmetric Synthesis of Nitrogen-Containing Compounds: How and Why
Author(s) -
Luca Bernardi,
Francesco Fini,
Mariafrancesca Fochi,
Alfredo Ricci
Publication year - 2007
Publication title -
chimia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 55
eISSN - 2673-2424
pISSN - 0009-4293
DOI - 10.2533/chimia.2007.224
Subject(s) - organocatalysis , strecker amino acid synthesis , chemistry , organic synthesis , nitrogen , enantioselective synthesis , organic chemistry , catalysis , combinatorial chemistry , biochemical engineering , engineering
Various types of polyfunctionalised stereodefined organic molecules appear to be highly serviceable as organocatalysts in the asymmetric synthesis of nitrogen-containing compounds. Beyond name reactions such as the aza-Henry, the Friedel-Crafts, and the Strecker other representative transformations like the hydrophosphonylation can be easily approached by using the suitable organocatalytic species and are herein reported with a special emphasis placed on the reaction and stereochemical outcomes and on the mechanistic insights