Open AccessDevelopment of Organometallic Ruthenium(II) Anticancer (RAPTA) Drugs
Author(s) -
Wee Han Ang
Publication year - 2007
Publication title -
chimia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 55
eISSN - 2673-2424
pISSN - 0009-4293
DOI - 10.2533/chimia.2007.140
Subject(s) - ruthenium , group 2 organometallic chemistry , chemistry , combinatorial chemistry , organic chemistry , catalysis , molecule
The systematic development of the RAPTA family of organometallic ruthenium(II) anticancer drugs containing a monodentate 1,3,5-triaza-7-phosphatricyclo-[3.3.1.1]decane (pta) ligand and a ?6-arene ligand is described.