Early Process Development: The Wyeth Approach | Zendy

Michael O’Brien | Zendy; Michael Kolb | Zendy; Karen Sutherland | Zendy; Kevin M. McCoy | Zendy; Anthony S. Pilcher | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Early Process Development: The Wyeth Approach

Author(s) -

Michael O’Brien,

Michael Kolb,

Karen Sutherland,

Kevin M. McCoy,

Anthony S. Pilcher

Publication year - 2006

Publication title -

chimia international journal for chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.387

H-Index - 55

eISSN - 2673-2424

pISSN - 0009-4293

DOI - 10.2533/chimia.2006.518

Subject(s) - context (archaeology) , productivity , process (computing) , phase (matter) , process management , computer science , operations management , biochemical engineering , process engineering , business , chemistry , engineering , history , economics , archaeology , economic growth , organic chemistry , operating system

The paper describes our approach to early process development in the context of the new Wyeth productivity model to deliver two New molecular entities every year. As a consequence, the number of compounds in Predevelopment and Phase 0 increased fourfold, the cycle time from Discovery to the IND was shortened by 6 months, and the quantities for the Phase-0 batch increased to include Phase I supply. our new way of working to meet this paradigm without a major increase in headcount is delineated in this article.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research