Open AccessEnantioselective Chromatography: an Essential and Versatile Tool for the Analytical and Preparative Separation of Enantiomers
Author(s) -
Eric Francotte
Publication year - 1997
Publication title -
chimia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 55
eISSN - 2673-2424
pISSN - 0009-4293
DOI - 10.2533/chimia.1997.717
Subject(s) - enantioselective synthesis , enantiomer , chemistry , chromatography , resolution (logic) , organic chemistry , computer science , catalysis , artificial intelligence
Chromatography on chiral stationary phases and electrophoresis in the presence of chiral selectors have become essential tools for the determination of enantiomeric purity in connection with synthesis and with biological studies of chiral molecules. Moreover, the chromatographic resolution of racemates on a preparative scale compels increasing recognition as alternative to 'preparing' pure enantiomers. The state-of-the-art of enantioselective chromatography in the analytical and preparative field is reviewed with particular emphasis on the achievements carried out in Switzerland.