Open AccessApplication of Enzymes in Industrial Organic Synthesis
Author(s) -
W. H. J. Boesten,
Quirinus B. Broxterman,
Eric C. Roos,
Bernard Kaptein,
W.J.J. van den Tweel,
J. Kamphuis,
E. M. Meijer,
Floris P. J. T. Rutjes,
Hans E. Schoemaker
Publication year - 1997
Publication title -
chimia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 55
eISSN - 2673-2424
pISSN - 0009-4293
DOI - 10.2533/chimia.1997.308
Subject(s) - aspartame , cefadroxil , dipeptide , amidase , chemistry , enzyme , ampicillin , organic chemistry , biochemistry , antibiotics , amino acid , cephalosporin
Aminopeptidase- and amidase-based methods for the production of enantiomerically pure amino acids, intermediates for pharmaceuticals and agrochemicals, are discussed. Furthermore, enzymatic syntheses of the dipeptide sweetener aspartame and semisynthetic antibiotics (such as ampicillin, amoxicillin, cephalexin, and cefadroxil) are highlighted.