Enantioselective Catalysis for Agrochemicals: The Case History of the DUAL MAGNUM® Herbicide | Zendy

HansUlrich Blaser | Zendy; Felix Spindler | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Enantioselective Catalysis for Agrochemicals: The Case History of the DUAL MAGNUM® Herbicide

Author(s) -

HansUlrich Blaser,

Felix Spindler

Publication year - 1997

Publication title -

chimia international journal for chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.387

H-Index - 55

eISSN - 2673-2424

pISSN - 0009-4293

DOI - 10.2533/chimia.1997.297

Subject(s) - enantioselective synthesis , catalysis , agrochemical , imine , organic chemistry , chemistry , iridium , combinatorial chemistry , biology , ecology , agriculture

The use of enantioselective catalytic methods for the technical preparation of chiral agrochemicals is illustrated by the case history of the herbicide (S)-merolachlor (trade name DUAL MAGNUM®). The key step for the technical synthesis of the enantiomerically enriched compound is the asymmetric hydrogenation of an imine intermediate, made possible by a new iridium-ferrocenyldiphosphine catalyst system. Important aspects of the development of the catalyst system as well as minimal prerequisites for the use of enantioselective catalysts for the production of agrochemicals are discussed.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research