Open AccessOrganic Synthesis with α-Silylcarbonyl Compounds
Author(s) -
Yannick Landais
Publication year - 1996
Publication title -
chimia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 55
eISSN - 2673-2424
pISSN - 0009-4293
DOI - 10.2533/chimia.1996.641
Subject(s) - synthon , organosilicon , silylation , organic synthesis , chemistry , organic chemistry , simple (philosophy) , combinatorial chemistry , nanotechnology , catalysis , materials science , philosophy , epistemology
Our interest in organosilicon compounds has led us to examine the chemistry of rarely used α-silylcarbonyl compounds. Possible applications of these synthons are not covered totally here, but a few examples along these lines should demonstrate the utility of these structurally simple substrates in organic synthesis. The preparation of the α-silyl esters and some examples of their stereocontrolled conversion into polysubstituted tetrahydrofurans is presented.