Cyclic Peptides as Topological Templates in Biomimetic Chemistry | Zendy

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Cyclic Peptides as Topological Templates in Biomimetic Chemistry

Author(s) -

Pascal Dumy

Publication year - 1996

Publication title -

chimia international journal for chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.387

H-Index - 55

eISSN - 2673-2424

pISSN - 0009-4293

DOI - 10.2533/chimia.1996.640

Subject(s) - template , raft , chemistry , combinatorial chemistry , bioorganic chemistry , molecule , nanotechnology , biochemistry , materials science , organic chemistry , polymer , copolymer , enzyme

Cyclic decapeptides containing up to four orthogonally protected lysine residues or selectively addressable faces represent a new class of Regioselectively Addressable Functionalized Templates (RAFT). We summarize here recent synthetic aspects and conformational properties of these constrained peptides along with potential applications for RAFT molecules in bioorganic chemistry and protein design.

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