Open AccessCyclic Peptides as Topological Templates in Biomimetic Chemistry
Author(s) -
Pascal Dumy
Publication year - 1996
Publication title -
chimia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 55
eISSN - 2673-2424
pISSN - 0009-4293
DOI - 10.2533/chimia.1996.640
Subject(s) - template , raft , chemistry , combinatorial chemistry , bioorganic chemistry , molecule , nanotechnology , biochemistry , materials science , organic chemistry , polymer , copolymer , enzyme
Cyclic decapeptides containing up to four orthogonally protected lysine residues or selectively addressable faces represent a new class of Regioselectively Addressable Functionalized Templates (RAFT). We summarize here recent synthetic aspects and conformational properties of these constrained peptides along with potential applications for RAFT molecules in bioorganic chemistry and protein design.