Open AccessHighly Efficient Lipase-Catalyzed Kinetic Resolution of Chiral Amines
Author(s) -
Manfred T. Reetz,
Claus Dreisbach
Publication year - 1994
Publication title -
chimia
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 55
eISSN - 2673-2424
pISSN - 0009-4293
DOI - 10.2533/chimia.1994.570
Subject(s) - kinetic resolution , lipase , catalysis , chemistry , kinetic energy , combinatorial chemistry , organic chemistry , enantioselective synthesis , enzyme , physics , quantum mechanics
The lipase Candida antarctica catalyzes the enantioselective acetylation of chiral primary amines, kinetic resolution leading to an enantiomeric excess (ee) of 90–98%.