Open AccessPharmaceutical Technology: Drug Delivery, Formulation, and Process Research
Author(s) -
Hans Leuenberger
Publication year - 2006
Publication title -
chimia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 55
eISSN - 2673-2424
pISSN - 0009-4293
DOI - 10.2533/000942906777675092
Subject(s) - pharmaceutical sciences , pharmaceutical industry , context (archaeology) , process analytical technology , pharmaceutical technology , pharmaceutical drug , management science , process (computing) , field (mathematics) , pharmaceutical engineering , computer science , nanotechnology , biochemical engineering , engineering , drug , materials science , medicine , mathematics , work in process , chemistry , pharmacology , operations management , paleontology , chromatography , pure mathematics , biology , operating system
This paper describes in the introduction the actual research trends in the area of pharmaceutical technology and the impact of FDA's PAT (Process Analytical Technology) Initiative on this research field. These new FDA requirements concerning a science-based approach in the area of pharmaceutical formulations and processes will boost this research field in academia and industry. There is a special need for a research initiative in the field of pharmaceutical powder technology, which is the basis for ca. 80% of all drug delivery systems on the market, i.e. solid dosage forms. Pharmaceutical formulations are complex systems which are difficult to model and analyse. For this purpose special tools such as the percolation theory, concept of fractal dimensions, dielectric spectroscopy, etc. are necessary. In this context, typical results obtained with these novel tools are presented.