
Transition Metal Catalysis for Pharmaceutical Intermediates and APIs
Author(s) -
Adriano F. Indolese,
Domenic Wasescha,
Thomas Eisele,
Christoph Bucher
Publication year - 2005
Publication title -
chimia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 55
eISSN - 2673-2424
pISSN - 0009-4293
DOI - 10.2533/000942905777676966
Subject(s) - carbonylation , transition metal , catalysis , toll , chemistry , portfolio , combinatorial chemistry , nanotechnology , business , organic chemistry , materials science , finance , carbon monoxide , biology , genetics
Rohner AG, a medium-sized Swiss company, has moved from toll manufacturing of building blocks and starting materials to the custom manufacturing of intermediates and APIs for the life science industry. Therefore, Rohner AG has expanded its technology portfolio to new technologies such as transition metal catalysis. Examples for asymmetric hydrogenation, Suzuki coupling and carbonylation are provided. In addition, the necessary changes in equipment and project management are presented and discussed.