Open AccessMicroarrays and Surface Engineering for Bioanalysis
Author(s) -
Hui Gao,
Sylvie Guinchard,
François Crevoisier,
Silvia Angeloni,
Hans Sigrist
Publication year - 2003
Publication title -
chimia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 55
eISSN - 2673-2424
pISSN - 0009-4293
DOI - 10.2533/000942903777678731
Subject(s) - bioanalysis , biomolecule , nanotechnology , surface modification , microanalysis , biocompatible material , covalent bond , chemistry , surface engineering , passivation , materials science , organic chemistry , engineering , biomedical engineering , layer (electronics)
Molecular engineering and covalent immobilization of biomolecules on material surfaces whilst retaining specificity and biological functions is a major challenge in bioarray manufacturing and analysis. Photochemical functionalization of materials enables specific bioengineering and facile manufacturing of biotech products for microanalysis with concomitant surface passivation. Surfaces engineered with polysaccharides render materials hydrophilic, biocompatible and generally applicable for probe molecule immobilization. Products and procedures described support microanalytical investigations in all '-omics' domains.