Open AccessDrugs and Driving: Analytical Strategy
Author(s) -
Marc Augsburger
Publication year - 2002
Publication title -
chimia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 55
eISSN - 2673-2424
pISSN - 0009-4293
DOI - 10.2533/000942902777680757
Subject(s) - chromatography , mass spectrometry , chemistry , identification (biology) , biochemical engineering , biology , engineering , botany
Consumption of psychoactive substances may impair driving performance. Because of the diversity of the substances, toxicologists have to develop analytical strategies which allow the detection and the quantification of drugs in biological samples. The analytical strategy described here is composed of three steps: screening, confirmation, and quantification. For screening, immunological tests and chromatography techniques (GC and HPLC) are often used. For confirmation, identification by means of mass spectrometry is required, and quantification is often realized through chromatographic techniques.